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| Cat No | BSPA-1074 |
| Conjugate | |
| Type | Polyclonal Antibody |
| Source | Rabbit |
| Size | 1 mg |
| Application | ELISA; IHC |
| Format | Liquid |
| Concentration | Please refer to the vial lable for the specific concentration. |
| Buffer | Supplied in PBS. |
| Species | Human |
| Storage | Store at -20 degree. Avoid repeted freeze/thaw cycl. |
| Synonyms | ATF4;activating transcription factor 4 (tax-responsive enhancer element B67);TXREB;cyclic AMP-dependent transcription factor ATF-4;CREB 2;TAXREB67;DNA-binding protein TAXREB67;cAMP response element-binding protein 2;cAMP-dependent transcription factor ATF-4;cAMP-responsive element-binding protein 2 |
| Purification | |
| Note | Tis product l is eeze eezeleezeegrrch useeze ly, no useeze huma, apeut agnost apcal. |
| MolecularWeight | |
| Description | |
| Background | This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. |