Rabbit anti-Human Huntingtin Monoclonal Antibody-单克隆抗体-北京百欧泰生物科技有限公司

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抗体产品
- 一抗
  - --|--|流式抗体
  - --|--|单克隆抗体
  - --|--|重组兔单抗
  - --|--|多克隆抗体
  - --|--|小分子抗原抗体
  - --|--|抗体对
  - --|--|标签抗体
  - --|--|修饰性抗体
  - --|--|其他抗体
- 二抗
- 试剂盒
  - --|--|标记试剂盒
  - --|--|其他试剂盒
  - --|--|标记染料
蛋白产品
生物材料
- 金属纳米材料
  - --|--|金纳米颗粒
  - --|--|金纳米棒
  - --|--|银纳米颗粒
  - --|--|金纳米海胆
  - --|--|碳纳米颗粒
  - --|--|特殊形状纳米颗粒
- 磁性微球
  - --|--|PS Magnetic Particles
  - --|--|Silica Magnetic Particles
  - --|--|Fe3O4 Magnetic Particles
  - --|--|Functionalized Magnetic Particles
  - --|--|Magnetic Particles Conjugates
  - --|--|Fe2O3 Magnetic Particles
  - --|--|UF Magnetic Particles
  - --|--|Conjugation Kit
  - --|--|Other Magnetic Particles
  - --|--|磁力架
- 单分散微球
  - --|--|聚苯乙烯微球
  - --|--|二氧化硅微球
  - --|--|PMMA 微球
  - --|--|PET 微球
  - --|--|PVA 微球
  - --|--|PVC 微球
  - --|--|DVB 微球
  - --|--|PP 微球
  - --|--|PE 微球
  - --|--|GMA 微球
  - --|--|PLA微球
  - --|--|PLGA微球
  - --|--|PLLA微球
  - --|--|PDLA微球
- 其他材料
  - --|--|上转换纳米颗粒
  - --|--|量子点
  - --|--|荧光微球
  - --|--|色谱填料
热销产品
- 猴痘相关产品
- 新冠相关产品
- 外泌体相关产品
- 常用试剂
  - --|--|转染试剂
  - --|--|ELISA-FCM试剂
  - --|--|WB试剂
  - --|--|IHC-ICC-IF试剂
  - --|--|载体材料

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Rabbit anti-Human Huntingtin Monoclonal Antibody

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Documentation
Citations

Cat No	BMA-995
Conjugate
Type	重组兔多抗
Source	Rabbit
Size	50 uL
Application	Immunogen
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Species	Human
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Synonyms	HD;IT15;HTT;Huntingtin
Purification	Affinity purification
MolecularWeight	350kDa
Description
Background	Huntingtin is a disease gene linked to Huntingtons disease, a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded, unstable trinucleotide repeat in the huntingtin gene, which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9-35) has been identified in normal controls, and repeat numbers in excess of 40 have been described as pathological. The huntingtin locus is large, spanning 180 kb and consisting of 67 exons. The huntingtin gene is widely expressed and is required for normal development. It is expressed as 2 alternatively polyadenylated forms displaying different relative abundance in various fetal and adult tissues. The larger transcript is approximately 13.7 kb and is expressed predominantly in adult and fetal brain whereas the smaller transcript of approximately 10.3 kb is more widely expressed. The genetic defect leading to Huntingtons disease may not necessarily eliminate transcription, but may confer a new property on the mRNA or alter the function of the protein. One candidate is the huntingtin-associated protein-1, highly expressed in brain, which has increased affinity for huntingtin protein with expanded polyglutamine repeats. This gene contains an upstream open reading frame in the 5 UTR that inhibits expression of the huntingtin gene product through translational repression.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

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单克隆抗体

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Rabbit anti-Human Huntingtin Monoclonal Antibody