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Rabbit Anti-LMNA Polyclonal Antibody

Cat NoBSPA-2195
Conjugate
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; WB; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsLMNA;lamin A/C;FPL;IDC;LFP;CDDC;EMD2;FPLD;HGPS;LDP1;LMN1;LMNC;PRO1;CDCD1;CMD1A;FPLD2;LMNL1;CMT2B1;LGMD1B;lamin;70 kDa lamin;prelamin-A/C;lamin A/C-like 1;renal carcinoma antigen NY-REN-32
Purification
NoteTis product l is eeze eezeleezeegrrch useeze ly, no useeze huma, apeut agnost apcal.
MolecularWeight
Description
BackgroundLamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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