中文English Call: 400-669-8850 | E-mail: info@biotyscience.com

修饰性抗体

当前位置:首页 >>产品中心 >>抗体产品 >>一抗 >>修饰性抗体

Contact us

Biotyscience Inc

Tel 400-669-8850

E-mail info@biotyscience.com

QQ  499854788

       82458988


Rabbit anti-Human Phospho-Smad1-S206 Polyclonal Antibody

Cat NoBPA-17088
Conjugate
TypePhosphorylated Antibody
SourceRabbit
Size50 uL
ApplicationIHC; IF
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS with 0.02% sodium azide,50% glycerol,pH7.3.
SpeciesHuman
StorageStore at -20℃. Avoid freeze / thaw cycles.
SynonymsBSP-1;BSP1;JV4-1;JV41;MADH1;MADR1;Smad1;SMAD1
PurificationAffinity purification
MolecularWeight60KDa
Description
BackgroundThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
客服:
400-669-8850
产品:
177-3110-0244
服务:
136-8125-6816
QQ 在线咨询

微信二维码
电子邮箱
info@biotyscience.com