Rabbit anti-Human Phospho-Chk2-S516 Polyclonal Antibody-修饰性抗体-北京百欧泰生物科技有限公司

Content

抗体产品
- 一抗
  - --|--|流式抗体
  - --|--|单克隆抗体
  - --|--|重组兔单抗
  - --|--|多克隆抗体
  - --|--|小分子抗原抗体
  - --|--|抗体对
  - --|--|标签抗体
  - --|--|修饰性抗体
  - --|--|其他抗体
- 二抗
- 试剂盒
  - --|--|标记试剂盒
  - --|--|其他试剂盒
  - --|--|标记染料
蛋白产品
生物材料
- 金属纳米材料
  - --|--|金纳米颗粒
  - --|--|金纳米棒
  - --|--|银纳米颗粒
  - --|--|金纳米海胆
  - --|--|碳纳米颗粒
  - --|--|特殊形状纳米颗粒
- 磁性微球
  - --|--|PS Magnetic Particles
  - --|--|Silica Magnetic Particles
  - --|--|Fe3O4 Magnetic Particles
  - --|--|Functionalized Magnetic Particles
  - --|--|Magnetic Particles Conjugates
  - --|--|Fe2O3 Magnetic Particles
  - --|--|UF Magnetic Particles
  - --|--|Conjugation Kit
  - --|--|Other Magnetic Particles
  - --|--|磁力架
- 单分散微球
  - --|--|聚苯乙烯微球
  - --|--|二氧化硅微球
  - --|--|PMMA 微球
  - --|--|PET 微球
  - --|--|PVA 微球
  - --|--|PVC 微球
  - --|--|DVB 微球
  - --|--|PP 微球
  - --|--|PE 微球
  - --|--|GMA 微球
  - --|--|PLA微球
  - --|--|PLGA微球
  - --|--|PLLA微球
  - --|--|PDLA微球
- 其他材料
  - --|--|上转换纳米颗粒
  - --|--|量子点
  - --|--|荧光微球
  - --|--|色谱填料
热销产品
- 猴痘相关产品
- 新冠相关产品
- 外泌体相关产品
- 常用试剂
  - --|--|转染试剂
  - --|--|ELISA-FCM试剂
  - --|--|WB试剂
  - --|--|IHC-ICC-IF试剂
  - --|--|载体材料

Contact us

Biotyscience Inc

Tel 400-669-8850

E-mail info@biotyscience.com

QQ 499854788

82458988

Rabbit anti-Human Phospho-Chk2-S516 Polyclonal Antibody

Description
Documentation
Citations

Cat No	BPA-17206
Conjugate
Type	Phosphorylated Antibody
Source	Rabbit
Size	50 uL
Application	WB
Format	Liquid
Concentration	Please refer to the vial lable for the specific concentration.
Buffer	Supplied in PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Species	Human
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Synonyms	CDS1;CHK2;HuCds1;LFS2;PP1425;RAD53;hCds1;CHEK2;Chk2
Purification	Affinity purification
MolecularWeight	62kDa
Description
Background	In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, the encoded protein is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein is a member of the CDS1 subfamily of serine/threonine protein kinases. Several transcript variants encoding different isoforms have been found for this gene.

We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.

上一篇：Rabbit anti-Human Phospho-STK11-T189 Polyclonal Antibody 下一篇：Rabbit anti-Human Phospho-BCR-Y177 Polyclonal Antibody

修饰性抗体

Content

Download

Contact us

Rabbit anti-Human Phospho-Chk2-S516 Polyclonal Antibody