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Rabbit anti-Human Acetyl-DNMT1-K1127/K1129/K1131/K1133 Polyclonal Antibody

Cat NoBPA-17655
Conjugate
TypeAcetylated Antibody
SourceRabbit
Size50 uL
ApplicationWB; IHC; IF; ChIP
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS with 0.02% sodium azide,50% glycerol,pH7.3.
SpeciesHuman
StorageStore at -20℃. Avoid freeze / thaw cycles.
SynonymsADCADN;AIM;CXXC9;DNMT;HSN1E;MCMT;m.HsaI;DNMT1
PurificationAffinity purification
MolecularWeightRefer to figures
Description
BackgroundThis gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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