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Cat No | BIOS-0272F |
Conjugate | |
Type | 流式抗体 |
Clone | M5E2 |
Source | Mouse |
Tag | APC |
Size | 1 mg |
Application | FCM |
ApplicationNote | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Format | Liquid |
Purity | >90% |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS; pH 7.4. |
Storage | Store at -20 degree for long term. |
Synonyms | Monocyte differentiation antigen CD14;CD14;Myeloid cell-specific leucine-rich glycoprotein |
Purification | SDS-PAGE |
MolecularWeight | |
Description | |
Background | CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens, and in the upregulation of adhesion molecules and expression of cytokines in monocytes and neutrophils. |