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Mouse Anti-Human CD122/IL-2RB Antibody(Clone TU27), FITC

Cat NoBIOS-1162F
Conjugate
Type流式抗体
CloneTU27
SourceMouse
TagFITC
Size1 mg
ApplicationFCM
ApplicationNoteEach lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
FormatLiquid
Purity>90%
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS; pH 7.4.
StorageStore at -20 degree for long term.
SynonymsInterleukin-2 receptor subunit beta;Il2rb;IL-2 receptor subunit beta;IL-2R subunit beta;IL-2RB;High affinity IL-2 receptor subunit beta;p70-75;CD122
PurificationSDS-PAGE
MolecularWeight
Description
BackgroundCD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
We can provide a variety of products such as diagnostic proteins; target proteins; cytokines; etc.
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