Biotyscience Inc
Tel 400-669-8850
E-mail info@biotyscience.com
QQ 499854788
82458988
Cat No | BIOS-2641F |
Conjugate | |
Type | 流式抗体 |
Clone | 2F1 |
Source | Syrian |
Tag | PE/Cyanine7 |
Size | 1 mg |
Application | FCM |
ApplicationNote | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results (Clone The recommended concentration is 0.1-1 渭g/106聽cells in 100 渭L volume). |
Format | Liquid |
Purity | >90% |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS; pH 7.4. |
Storage | Store at -20 degree for long term. |
Synonyms | MAFA;2F25-Ag |
Purification | SDS-PAGE |
MolecularWeight | |
Description | |
Background | Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag).? KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3.? It is composed of a homodimer of glycosylated 30-38 kD subunits.? Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells.? KLRG1 is also expressed on subsets of CD8+?and CD4+?cells, including CD4+?and CD8+?effector/memory cells, potent regulatory CD4+?T cells.? KLRG1 may be involved in regulating NK cell homeostasis.? KLRG25 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells. |