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Cat No | ADMD-105 |
Conjugate | |
Type | 重组蛋白 |
Source | HEK293 |
Tag | His |
Size | 1mg |
Application | Immunology |
Format | Liquid |
Purity | >95 %, SDS-PAGE |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS |
Species | Rat |
Storage | Store at -20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | IFNG, IFN-gamma, IFN-γ, Interferon gamma |
Purification | Protein A/G |
Note | For research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. |
MolecularWeight | 18 kDa |
Description | |
Background | The IFNs were originally discovered as agents that interfere with viral replication. Initially, they were classified by the secreting cell type but are now classified into type I and type II according to receptor specificity and sequence homology. Interferon gamma (Ifng) is a soluble cytokine that is the only member of the type II class of interferons. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant Ifng expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB). Mutations in this gene are associated with aplastic anemia. |