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Cat No | BIOP035 |
Conjugate | |
Type | Recombinant Protein |
Source | N/A |
Tag | N/A |
Size | 0.1ml |
Application | Immunology |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | PBS |
Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
Synonyms | B CK;B CK;B-CK;BB-CK;BCK;Brain creatine kinase;Ckb;CKBB;CK-BB;Creatine kinase B;Creatine kinase B chain;Creatine kinase B-type;Creatine Kinase BB Isoenzyme;Creatine Kinase BB Isoenzyme;Creatine Kinase BB Isoenzyme;Creatine kinase brain;Creatine phosphokinase BB;KCRB_HUMAN. |
Purification | Affinity chromatography |
MolecularWeight | 43kDa |
Description | |
Background | The protein encoded by this gene, CK-BB, consists of a homodimer of two identical brain-type CK-B subunits. BB-CK is a cytoplasmic enzyme involved in cellular energy homeostasis, with certain fractions of the enzyme being bound to cell membranes, ATPases, and a variety of ATP-requiring enzymes in the cell. There, CK-BB forms tightly coupled microcompartments for in situ regeneration of ATP that has been used up. The encoded protein reversibly catalyzes the transfer of "energy-rich" phosphate between ATP and creatine or between phospho-creatine (PCr) and ADP. Its functional entity is a homodimer (CK-BB) in brain and smooth muscle as well as in other tissues and cells such as neuronal cells, retina, kidney, bone, etc. In heart, a heterodimer (CK-MB) shahil consisting of one CK-B brain-type CK subunit and one CK-M muscle-type CK subunit is prominently expressed. The encoded CK-BB and CK-MB proteins are members of the ATP:guanido phosphotransferase protein family. |