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Recombinant Human TNFSF8 Protein(aa 99-330), Fc-His

Cat NoBIOP1983
Conjugate
TypeTNF
SourceHEK293
TagFc-His
Size10 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS, pH 7.4. Normally 5 % - 19 % trehalose is added as protectants before lyophilization.
SpeciesHuman
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
SynonymsCD30-L;CD153;TNFSF8;CD30L;CD30LG;CD153 antigen;CD30 antigen ligand;CD30 Ligand
Purification> 95% by SDS-PAGE.
MolecularWeight
Descriptionaa 99-330
BackgroundThe protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkins and some non-Hodgkins lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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