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Cat No | BIOP2230 |
Conjugate | |
Type | 免疫检查点 |
Source | E. coli |
Tag | GST |
Size | 10 ug |
Application | Immunogen |
Format | Liquid |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in 20mM PB, 1mM EDTA, 5mM p-ME, 5%Trehalose, 400mM Nacl, pH6.5 |
Species | Mouse |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | Galectin-9;Lgals9;Gal-9 |
Purification | > 90 % as determined by SDS-PAGE |
MolecularWeight | |
Description | aa 1-322 |
Background | Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkins disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1. |