中文English Call: 400-669-8850 | E-mail: info@biotyscience.com

重组蛋白

当前位置:首页 >>产品中心 >>蛋白产品 >>重组蛋白

Contact us

Biotyscience Inc

Tel 400-669-8850

E-mail info@biotyscience.com

QQ  499854788

       82458988


Recombinant Mouse PD-L1/B7-H1 Protein(aa 1-238), His

Cat NoBIOP2248
Conjugate
Type免疫检查点
SourceHEK293
TagHis
Size20 ug
ApplicationImmunogen
FormatLyophilized
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS, pH 7.4.
SpeciesMouse
StorageStore at –20 degree. Avoid repeated freeze/thaw cycles.
SynonymsPD-L1;CD274;B7-H1;PDCD1L1;PDCD1LG1
Purification> 95% by SDS-PAGE.
MolecularWeight
Descriptionaa 1-238
BackgroundProgrammed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1). PD-L1/B7-H1 is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. PD-L1/B7-H1 is a member of the growing B7 family of immune molecules that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
客服:
400-669-8850
产品:
177-3110-0244
服务:
136-8125-6816
QQ 在线咨询

微信二维码
电子邮箱
info@biotyscience.com