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Cat No | BIOP3311 |
Conjugate | |
Type | 细胞培养 |
Source | HEK293 |
Tag | His |
Size | 20 ug |
Application | Immunogen |
Format | Lyophilized |
Concentration | Please refer to the vial lable for the specific concentration. |
Buffer | Supplied in PBS, pH 7.4. |
Species | Rat |
Storage | Store at –20 degree. Avoid repeated freeze/thaw cycles. |
Synonyms | DIF;TNF-alpha;TNFA;TNFSF2;cachexin;cachectin;TNFα |
Purification | > 95% by SDS-PAGE. |
MolecularWeight | |
Description | |
Background | Tumor necrosis factor alpha is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimers disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin.TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment. |