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重组蛋白

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Recombinant Human GITR Protein, Fc

Cat NoBSA-1033
Conjugate
Type重组蛋白
SourceHEK293
TagFc
Size1mg
ApplicationImmunology
Purity≥95%, SDS-PAGE
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS with 6% Mannitol, pH7.4.
StorageStore at -20 degree for long time. Avoid repeated freeze/thaw cycles.
SynonymsAITR;GITR;TNFRSF18;CD357
PurificationChromatography
MolecularWeight41.5kD
Description内毒素<0.1EU/ug
BackgroundGITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases. It also mediates NF-kappa-B activation via the TRAF2/NIK pathway.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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