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Rabbit Anti-AAK1 Polyclonal Antibody

Cat NoBSPA-0446
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; WB; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsAAK1;AP2 associated kinase 1;AP2-associated protein kinase 1;DKFZp686K16132;KIAA1048;adaptor-associated kinase 1;FLJ23712;FLJ25931;FLJ31060;FLJ42882;FLJ45252;MGC138170;MGC164568;MGC164570;DKFZp686F03202
NoteThis product as lupplied is intnded for rlarch us only, not for us in human, therapeutic or diagnostic applicationl.
BackgroundAdaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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