中文English Call: 400-669-8850 | E-mail: info@biotyscience.com

可以介绍下你们的产品么

你们是怎么收费的呢

现在有优惠活动吗

请您留言

感谢您的关注,请填写一下您的信息,我们会尽快和您联系。

提交

产品中心

当前位置:首页 >>产品中心

Content

Contact us

Biotyscience Inc

Tel 400-669-8850

E-mail info@biotyscience.com

QQ  499854788

       82458988


Rabbit Anti-CD209 Polyclonal Antibody

Cat NoBSPA-1552
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; WB; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsCD209;CDSIGN;CLEC4L;DC-SIGN;DC-SIGN1
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
BackgroundPathogen-recognition receptor expressed on the surface of immature dendritic cells and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens, including HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, cytomegalovirus gB, HCV E2, dengue virus gE, Leishmania pifanoi LPG, Lewis-x antigen in Helicobacter pylori LPS, mannose in Klebsiella pneumonae LPS, di-mannose and tri-mannose in Mycobacterium tuberculosis ManLAM and Lewis-x antigen in Schistosoma mansoni SEA. On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to regulate DC-induced T-cell proliferation by binding to ICAM3 on T-cells in the immunological synapse formed between DC and T-cells.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
咨询热线:
客服:400-669-8850 产品:177-3110-0244 服务:136-8125-6816
在线客服:
产品咨询-1点击这里给我发消息QQ交谈
服务咨询-2点击这里给我发消息QQ交谈
微信二维码:
公司官网: www.biotyscience.com