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Rabbit Anti-CFB Polyclonal Antibody

Cat NoBSPA-1626
TypePolyclonal Antibody
SourceRabbit
Size1 mg
ApplicationELISA; IHC
FormatLiquid
ConcentrationPlease refer to the vial lable for the specific concentration.
BufferSupplied in PBS.
SpeciesHuman
StorageStore at -20 degree. Avoid repeted freeze/thaw cycl.
SynonymsCFB;complement factor B;BF;FB;BFD;GBG;CFAB;CFBD;PBF2;AHUS4;FBI12;H2-Bf;ARMD14;C3 proactivator;C3/C5 convertase;C3 proaccelerator;properdin factor B;B-factor, properdin;glycine-rich beta glycoprotein;glycine-rich beta-glycoprotein
NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
BackgroundFactor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
We can offer labeled proteins/antibodies using a broad range of intensely fluorescent dyes and labels including FITC, Biotin, Alexa Fluor, Rhodamine B, Cy, Co-Au.
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